All Conditions
We Evaluate
Ketamine therapy for mental health and chronic pain — 20 conditions, one clinic
Conditions ketamine treats in Baltimore span 20 diagnoses — from $499.99 per session ($375 for Vitality Circle members) for mental health and $1,499.99 ($1,125 member) for chronic pain — delivered as anesthesiologist-led care, under the medical direction of Dr. Brijen Joshi MD, a Johns Hopkins anesthesiologist, with a Certified Registered Nurse Anesthetist (CRNA) on-site. Mental health conditions include treatment-resistant depression, PTSD, anxiety, bipolar depression, OCD, and postpartum depression; chronic pain conditions include fibromyalgia, neuropathy, chronic back pain, migraines, arthritis, and sciatica. Ketamine therapy is off-label for these indications — prescribed on individual physician clinical judgment, not as an FDA-approved treatment per condition — and self-pay, with an itemized superbill you can file with your insurance. Chronic pain infusions are longer, higher-dose sessions, and a driver is required after every ketamine session. Not everyone is a candidate; individual eligibility requires clinical evaluation, and you'll be told clearly.
"The team is extremely professional, compassionate and knowledgeable — they take the time to explain the process thoroughly and care about your well-being throughout." — Google review, Vita Nova patient
Founder & Medical Director, Vita Nova · Johns Hopkins Faculty Physician · Assistant Professor, Anesthesiology & Critical Care Medicine · Chief, Thoracic Anesthesia, Johns Hopkins Hospital · Board-Certified Anesthesiologist
LegitScript CertifiedMon–Fri: 1PM–8PM · Sat: 10AM–2PM
513 Bayview Blvd, Canton Baltimore MD 21224
(443) 563-1059
All Conditions We Evaluate
Vita Nova evaluates adults whose conditions have not responded adequately to prior treatments. Select a category to explore the conditions we evaluate — each links to a dedicated condition page with clinical detail, eligibility guidance, and pricing. Each family also has its own hub: ketamine for mental health conditions in Baltimore and ketamine for chronic pain in Baltimore.
Major depression that has not responded to 2+ adequate antidepressant trials. The most common reason patients seek ketamine therapy, given its rapid-onset NMDA mechanism.
View condition page →Post-traumatic stress disorder — intrusive memories, avoidance, and hyperarousal patterns addressed through ketamine's NMDA mechanism when standard treatments have not achieved adequate response.
View condition page →Generalized anxiety disorder, social anxiety, and panic disorder evaluated when SSRIs, SNRIs, and therapy have not produced adequate relief.
View condition page →Major depressive disorder with acute suicidal ideation, where the rapid onset of ketamine's effect is clinically relevant. Evaluated individually with appropriate crisis coordination.
View condition page →Depressive episodes in bipolar disorder that often do not respond to standard antidepressant monotherapy. Evaluated with review of mood stabilization and current medication regimen.
View condition page →Obsessive-compulsive disorder that has not responded adequately to serotonin reuptake inhibitors and behavioral therapy protocols.
View condition page →Severe postpartum depression not responding to standard treatments. Requires review of breastfeeding status, concurrent medications, and obstetric care coordination.
View condition page →Affective blunting — often a feature of treatment-resistant depression or SSRI side effects. Evaluated as part of a broader care pathway when impacting quality of life significantly.
View condition page →Evaluated on a case-by-case basis only for patients in documented stable recovery, with comprehensive review of substance use history and addiction specialist coordination.
View condition page →Overlapping mental health and chronic pain presentations where NMDA blockade may address both dimensions simultaneously through a unified mechanism.
View condition page →Widespread musculoskeletal pain with central sensitization as a core mechanism — one of the chronic pain conditions most directly aligned with ketamine's NMDA-blocking mechanism.
View condition page →Chronic pain of 3 months or more with a central sensitization component. Evaluated when structural or pharmaceutical approaches have not achieved adequate relief.
View condition page →Persistent back pain with a central sensitization component — evaluated when physical therapy, injections, or other interventional approaches have not resolved the pain experience.
View condition page →Refractory migraine and chronic daily headache evaluated when standard preventive and abortive treatments have not achieved adequate control.
View condition page →Peripheral and central neuropathic pain from diabetic neuropathy, post-herpetic neuralgia, chemotherapy-induced neuropathy, and other causes.
View condition page →Persistent joint pain from osteoarthritis and inflammatory arthritis with a central sensitization component not fully addressed by anti-inflammatory approaches.
View condition page →Chronic sciatic nerve pain and radiculopathy evaluated when structural management — including injections and physical therapy — has not resolved the pain experience.
View condition page →Pelvic floor pain and CPPS where central sensitization is increasingly recognized as a significant mechanism. Evaluated with full gynecologic and urologic history review.
View condition page →Persistent pain following surgery where central sensitization has developed. Evaluated when standard post-operative pain management has not been sufficient.
View condition page →Widespread inflammatory pain where NMDA-mediated central amplification contributes significantly to the pain burden alongside peripheral inflammation.
View condition page →Why One Treatment Addresses Both
Ketamine's clinical relevance across such a broad range of conditions — both mental health and pain-related — is not coincidental. Both share a common underlying mechanism: central sensitization, a state in which the central nervous system becomes abnormally amplified in its response to signals. Ketamine's primary mechanism of action directly targets this process.
- The brain's limbic and prefrontal circuits responsible for mood regulation become dysregulated through excessive NMDA receptor activity and glutamate dysfunction
- Ketamine blocks NMDA receptors and rapidly increases glutamate signaling, promoting synaptogenesis — the formation of new synaptic connections in these circuits
- This explains the rapid-onset effect — within hours to days — compared to SSRIs and SNRIs which require weeks of daily dosing
- Relevant for: TRD, PTSD, anxiety, OCD, bipolar depression, postpartum depression, and co-occurring presentations
- Chronic pain conditions increasingly involve central sensitization — where spinal cord and brain pain-processing circuits amplify signals beyond what peripheral tissue damage would explain
- NMDA receptors are central mediators of this sensitization process in the dorsal horn of the spinal cord
- By blocking these receptors, ketamine disrupts the central amplification of pain signals — reducing the pain burden even when the peripheral source has not resolved
- Relevant for: fibromyalgia, neuropathy, CRPS, migraines, inflammatory pain, and post-surgical pain
Clinical evidence: Duman & Aghajanian 2012, Science (PMID 23042884) and Murrough et al. 2013, two-site randomized controlled trial (PMID 23982301) on ketamine's synaptogenic and rapid antidepressant effects; Woolf & Salter 2000, Science (PMID 10846153) on central sensitization; and the 2018 ASRA/AAPM/ASA consensus guidelines on IV ketamine for chronic pain, Cohen et al., Reg Anesth Pain Med (PMID 29870458). Individual results vary. Ketamine therapy is off-label for these indications. Eligibility requires individual clinical evaluation.
Rule Out the Physical Drivers — Iron Infusion & IV Therapy
Low mood, brain fog, and persistent exhaustion are not always purely mental health symptoms. Iron-deficiency anemia produces fatigue, poor concentration, and low mood that can mimic or compound depression — and it is frequently missed. Before assuming a symptom is purely psychological, it is worth ruling out the physical contributors. Vita Nova offers Iron IV infusion for diagnosed iron deficiency when oral iron has been insufficient or poorly tolerated, alongside a full menu of IV vitamin therapy for energy, immune, and recovery support.
- Replenishes iron stores when oral iron has failed or caused GI side effects
- Targets the fatigue, brain fog, and low mood of iron-deficiency anemia at the physical root
- $425.99–$799.99 · dosing and duration confirmed at clinical review · 25% off for members
- View Iron IV infusion page →
- 13 formulas including Myers' Cocktail, NAD+, High-Dose Vitamin C, and Immunity Boost
- Supports energy, immune resilience, and recovery — no driver required for wellness IVs
- Standard IVs $139.99–$199.99 · one standard IV included each month for Vitality Circle members
- View the full IV therapy menu →
Am I a Candidate — What We Look For
Ketamine therapy is not appropriate for every patient, and not every patient who completes evaluation is offered a care pathway. The following framework gives a general sense of eligibility — your specific situation is reviewed individually during evaluation.
- Adults (18+) with a qualifying diagnosis of a mental health or chronic pain condition
- Documented history of 2 or more prior treatments that did not produce adequate response
- Physically located in Maryland for telemedicine consultation
- Able to arrange a driver for every in-clinic session
- No active contraindications identified during medical history review
- Willing to coordinate care with existing mental health or medical providers
- Uncontrolled hypertension or unstable cardiovascular conditions
- Active or personal history of psychosis or primary psychotic disorders
- Personal or family history of schizophrenia
- Active substance use disorder (addiction recovery cases reviewed case-by-case)
- Current high-dose benzodiazepine use
- Pregnancy
- Personal history of ketamine or dissociative drug abuse
Important: this is a general framework only. The presence of one or more contraindications does not automatically disqualify you — and the absence of contraindications does not guarantee eligibility. A comprehensive clinical evaluation is required for every patient. The first step is a telemedicine consultation. Book yours here →
All 20 Conditions — Direct Links
Every condition evaluated at Vita Nova has a dedicated page with clinical detail, NMDA mechanism explanation, eligibility guidance, and pricing.
All conditions are evaluated for ketamine infusions. Ketamine therapy is off-label for these indications — individual clinical evaluation required for all.
Conditions & Eligibility — Questions Answered
The most common questions patients ask about which conditions Vita Nova evaluates and how eligibility is determined.
Ready to Discuss
Your Condition?
A telemedicine consultation is the first step. Our clinical team reviews your complete history — diagnosis, prior treatments, current medications — and determines whether any care pathway is appropriate. No commitment required.
Canonical URL: https://vitanovawellnessclinic.com/all-conditions-treated/ · Last reviewed August 2026
